Çalışma Alanları
- Sağlık Bilimleri Temel Alanı
- Farmasotik Kimya
- Synthesis and Anticancer Activity of Novel Indole Derivatives as Dual EGFR/SRC Kinase Inhibitors, 2024
- Determination of Novel SARS-CoV-2 Inhibitors by Combination of Machine Learning and Molecular Modeling Methods, 2024
- Investigating the Activity of Indole-2-on Derivative Src kinase inhibitors against Chronic Myeloid Leukemia Cells, 2023
- Antimicrobial Evaluation, Molecular Docking and ADME Properties of Indole Amide Derivatives, 2022
- Synthesis of Novel Urea and Sulfonamide Derivatives of Isatin Schiff Bases as Potential Anti-cancer Agents, 2022
- A Prospective Overview of Drug Repurposing in Drug Discovery and Development, 2019
- Drug Repurposing in the Development of Anticancer Agents., 2019
- Overview on Anticancer Drug Design and Development, 2018
- In Vitro Antibacterial and Antifungal Activity and Computational Evaluation of Novel Indole Derivatives Containing 4-Substituted Piperazine Moieties, 2018
- SAHAquines, Novel Hybrids Based on SAHA and Primaquine Motifs, as Potential Cytostatic and Antiplasmodial Agents, 2018
- Synthesisi and Antioxidant Activity of Indole Derivatives Containing 4-Substituted Piperazin Moieties, 2017
- Design Strategies Structures and Molecular Interactions of Small Molecule SrcInhibitors, 2016
- The Effects of 1 3 5 trisubstituted Indole Derivatives on Cell Growth Apoptosis and MMP 2 9 mRNA Expression of MCF 7 Human Breast Cancer Cells, 2016
- N 3 Substituted benzylidene 2 oxoindolin 5 yl acetamide Derivatives as Src Inhibitors Syntheis Biological Evaluation and Molecular Dockimg, 2015
- Synthesis Biological and Computational Evaluation of 1 3 5 Substituted Indol 2 on Derivatives as Src Kinase Inhibitors, 2015
- Kozmetikler ve İn Sliko Yaklaşımlar, 2014
- Recent development of new substituted indole and azaindole derivatives as anti HIV agents, 2013
- Molecular Modeling Based Approach and In Vitro Assay of N Substituted Indole 2 and 3 Carboxamide Derivatives as Human Protein Kinase CK2 Inhibitors, 2013
- Synthesis of new indole 2 carboxamide and 3 acetamide derivatives and evaluation their antioxidant properties, 2013
- Synthesis Biological and Computational Evaluation of Novel Oxindole Derivatives as Inhibitors of Src Family Kinases, 2013
- Synthesis and Biological Study of Novel Indole 3 imine 2 on Derivatives as Src Kinases and Glutathione S Transferase Inhibitors, 2013
- Synthesis biological evaluation and docking studies of new pyrrolo 2 3 d pyrimidine derivatives as Src family selective tyrosine kinase inhibitors, 2013
- Design Src Kinase Inhibitors as a Therapeutic Approach for Cancer and Metastases, 2011
- Structure activity evaluation of N benzyl 5 substituted indole 3 imine derivatives and their amine congeners as bovine testicular hyaluronidase BTH inhibitor, 2011
- Indole derivatives as src family kinase and glutathione s transferase inhibitors evaluation of their selectivity and drug resistance properties, 2011
- Synthesis of Novel Oxoindole Derivatives as Inhibitors of c Src Tyrosine Kinase, 2011
- Synthesis of new pyrrolo 2 3 d pyrimidine derivatives as Src Kinase Inhibitors, 2011
- Autodisplay of catalically active human hyaluronidase hPH 20 and testing of enzyme inhibitors, 2011
- Evaluation of Novel Aminomethylindole Derivatives as Src Kinase Inhibitors and Antioxidant Agents, 2011
- Effect of Novel pp60c Src Inhibitors on Mammalian Glutation S Transferase Activity, 2010
- Cover Picture Role of fluorine substitution in biphenyl methylene imidazole type CYP17 inhibitors for the treatment of prostate carcinoma, 2010
- Role of fluorine substitution in biphenyl methylene imidazole type CYP17 inhibitors for the treatment of prostate carcinoma, 2010
- Investigation of Aminomethyl Indole Derivatives as Hyaluronidase Inhibitors, 2010
- N Substituted Indole 3 imine Derivatives and their Amine Congeners Antioxidant and Src Kinase Inhibitory Effects, 2010
- Novel Aminomethylindole Derivatives as Inhibitors of pp60c Src Tyrosine Kinase Synthesis and Biological Activity, 2009
- Evaluation of New Indole and Bromoindole derivatives as pp60c Src Tyrosine Kinase Inhibitors, 2009
- Synthesis and pp60c Src tyrosine kinase inhibitory activity of novel indole 3 imine derivatives and their amine congeners substituted at N1 and C5, 2009
- A study of 3 Substituted Benzylidene 1 3 Dihydro Indolin Derivatives as Antimicrobial and Antiviral Agents, 2009
- Kombinatoryal Bütünleştirici Kimya Kombinatoryal Sentez Yöntem ve Teknolojileri Kombinatoryal Kütüphaneler ve Yüksek Hızda Aktivite Tarama Yhat, 2008
- Synthesis biological evaluation and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17 hydroxylase 17 20 lyase CYP17 Part II Core rigidification and influence of substituents at the methylene bridge, 2008
- Antimicrobial and Antiviral Screening of Novel Indole Carboxamide and Propanamide Derivatives, 2008
- Synthesis and Evaluation of N Substituted Indole 3 Carboxamide Derivatives as Inhibitors of Lipid Peroxidation and Superoxide Anion Formation, 2008
- Synthesis and Activity of Novel 5 Substituted Pyrrolo 2 3 d pyrimidine Analogues as pp60c Src Tyrosine Kinase Inhibitors, 2008
- Site specific Modification of Shigella flexneri virF mRNA by tRNA Guanine Transglycosylase In vitro, 2007
- New Potent Indole Derivatives as Hyaluronidase Inhibitors, 2007
- In vitro Scavenging Activity for Reactive Oxygen Species by N Substituted indole 2 carboxylic Acid Esters, 2007
- Synthesis and Evaluation of Novel N H and N Substituted Indole 2 and 3 Carboxamide Derivatives as Possible Antioxidant Agents, 2007
- Synthesis of N substituted indole 2 carboxamides and investigation of their biochemical responses against free radicals, 2007
- Synthesis and Antioxidant Properties of Novel N H and N Substituted Propanamide Derivatives, 2007
- Synthesis and Biological Evaluation of 3 Substituted benzylidene 1 3 dihydro indolin Derivatives as Human Protein Kinase CK2 and p60c Src Tyrosine Kinase Inhibitors, 2007
- Comparison of some 3 substituted benzylidene 1 3 dihydro indolin derivatives as ligands of tyrosine kinase based on binding mode studies and biological assay, 2006
- Antiviral activity of nucleoside analogues against SARS coronavirus SARS Cov, 2006
- Synthesis of 3 substituted benzylidene 1 3 dihydro indolin derivatives and investigation of their roles against human protein kinase, 2006
- Synthesis and Antioxidant Properties of Novel N Substituted Indole 3 carboxamide Acetamide and Propanamide Derivaties, 2006
- Çeşitli İndol Türevlerinin p56Lck Tirozin Kinaz İnhibitörleri Olarak Doking Çalışmaları ile Analizi, 2005
- Scavenging of reactive oxgen species by novel 3 substituted benzylidine 1 3 dihydro indoline 2 one and 3 substituted benzylidine 1 3 dihydro indoline 2 thione derivatives, 2005
- Design and Synthesis of Novel Indole Deivatives as Anti angiogenic Agents, 2005
- Synthesis of Radiolabelled 5 Aminomethyl 2 aminopyrrolo 2 3 d pyrimidine 4 3H one PreQ1 and 2 Amino 5 1S 2R 3S 2 3 dihydroxycyclopent 4 enylamino methyl pyrrolo 2 3 d pyrimidine 4 3H one, 2005
- Synthesis and docking based studies of 3 substituted indolin 2 on and thione derivatives as tyrosine kinase inhibitors, 2005
- Antioxidant activity of N Substituted Indole 2 and 3 carboxamides, 2004
- A study On the Interaction Between p60c Src Receptor Tyrosine Kinase and Arylcarboxylic and Arylacetic Acid Derivatives Based On Docking Modes and In Vitro Bioactivity, 2004
- Scavenging of Reactive Species by N substituted indole 2 and 3 carboxamides, 2004
- Evaluations of Indole Esters as Inhibitors of p60c Src Receptor Tyrosine Kinase and Investigation of enzyme Inhibition Using Receptor Docking Studies, 2003
- Antioxidant Evaluations of Novel N H and N Substituted Indole Esters, 2003
- Synthesis and Biological Activity of 2 Deoxy 2 fluoro L arabinofuranosyl Imidazole Derivatives, 2002
- Evaluation of N H and N Substituted Indole 2 Carboxylic Acid Esters as Anti HIV Agents, 2002
- Angiogenesis and new aspects of cancer chemotheraphy, 2002
- Synthesis and Antioxidant Properties of Novel N Substituted indole 2 carboxamide and 3 acetamide Derivatives, 2002
- Synthesis and Biological Evaluation of N Substituted Indole Esters as Inhibitors of Cyclooxygenase 2 COX 2, 2002
- Syntheses and Biological Evaluation of Indole 2 and 3 Carboxamides A New Selective Cyclooxygenase 2 Inhibitors, 2002
- Synthesis and Anti HIV Activity of D 2 3 didehydro 2 3 dideoxy 2 fluoro 4 thiocytidines, 2002
- A Selective Search For Biologically Active BipartateNucleoside Prodrugs I, 2001
- Nucleosides as Anti Hepatitis B Virus Agents, 2001
- A Selective Search For Biologically Active Tripartate Nucleoside Prodrugs II, 2001
- Synthesis and Receptor Docking Studies of N substituted Indole 2 Carboxylic Acid Esters as a Search for Selective Enzyme İnhibitors, 2001
- Synthesis and Anti HIV Activity of L 2 3 Dideoxy 2 fluoro 4 thiocytidine, 2001
- Synthesis and Antiviral Activity of 2 Deoxy 2 fluoro L arabinofuranosyl 1 2 3 Triazole Derivatives, 2001
- Synthesis and Anti viral Activities of Oxaselenolane Nucleosides, 2000
- Synthesis and Anti Viral Activities of Enantiomeric Hydroxymethyl Cyclopropyl Methyl Nucleosides, 2000
- Enantiomeric Syntheses of Conformationally Restricted D and L 2 3 Dideoxy 2 3 endo methylene Nucleosides from Carbohydrate Chiral Templates, 2000
- Synthesis and Anti Viral Activities of Oxaselenolane Nucleosides, 1999
- Synthesis of New Analgesic Esters and Investigation of Some their Physicochemical Parameters, 1999
- A review of An Interesting Structural Example of Nonsteroidal Antiinflammatory agents Benorilate, 1998
- Synthesis of Some New Benzimidazole 5 6 Carboxylic Acids, 1995
- Düşünceden ruhsata yeni bir ilaç, 1994
- Studies on the Quantitative Analysis Methods of Indapamide, 1992
- AIDS ve İlaç Dünyasındaki Gelişmeler, 1988
- Design and Synthesis of Novel Indole Derivatives as Tyrosine Kinase Inhibitors, 2022
- In silico investigation of membrane transporter activity of indole derivatives as SRC tyrosine kinase inhibitors,
- DETERMINATION OF POTENTIAL CANDIDATES OF NOVEL UREA AND SULFONAMIDE DERIVATIVES OF ISATIN SCHIFF BASES AS RECEPTOR TYROSINE KINASE INHIBITOR BY MOLECULAR DOCKING STUDIES., 2021
- DESIGN, SYNTHESIS, ADME AND MOLECULAR DOCKING STUDIES OF NOVEL UREA AND SULFONAMIDE DERIVATIVES OF ISATINE AS POTENTIAL ANTICANCER AGENTS, 2021
- Cytotoxic and Antiproliferative Activity of N- (4-Chlorophenyl) -1 H-Indole-2-Carboxamide on Prostate and Osteosarcoma Cell Lines.,
- Drug repurposing in the Development of Anti-Cancer Agents, 2020
- Prediction of Ecotoxicity Profile of Indole Derivatives as Src Tyrosine Kınase Inhibitors-In silico Study, 2019
- Design, Synthesis and Cytotoxic Effects of Novel Pyrrolo Pyrimidine Derivatives, 2016
- Indole derivatives as src tyrosine kinases inhibitors – in silico prediction of metabolism mediated by cyp450 enzymes, 2019
- Adme predictions and safety profiles of indole derivatives as potential kinase inhibitors, 2019
- Prediction of the Safety Profile of Indole Derivatives as Src Tyrosine Kinase Inhibitors - Admet In Silico Study, 3rd International Symposium on Scientific and Regulatory Advances in Biological and Non–Biological Complex Drugs: A to Z in Bioequivalence, 2018
- In Silico Evaluation of Potential Carcinogenicity of Indole Derivatives as Src Tyrosine Kinases Inhibitors, 2019
- Comparison of Predicted Physicochemical Properties and In Vitro Activity of Substituted Indolin-2-one Derivatives, 2017
- Design Src Kinase Inhibitors as a Therapeutic Approach for Cancer and Metastases, 2011
- Designing small molecule src inhibitors through target based strategies using synthetic and molecular modeling techniques, 2012
- Design and synthesis novel small molecule src family kinase inhibitors, 2012
- Rational design of novel indolin 2 one derivatives as inhibitors of src family kinases, 2013
- Molecular Modeling Based Approach and Synthesis of Indole Derivatives as Src Kinase Inhibitors, 2013
- Kozmetik Moleküllerin Akılcı Tasarım Yöntemleri,
- Design Small Molecule Indole Derivatives as Src Kinase Inhibitors, 2015
- Kemoinformatik ve İlaç Tasarımı, 2016
- Synthesis Biological Activity and Docking Studies of Novel 3 substituted benzylidene 4 Fluorophenyl Indole 2 one Derivatives as Src Kinase Inhibitors, 2014
- Novel Indolin 2 on Derivatives as c Src Tyrosine Kinase Inhibitors Synthesis Biological Evaluation and Molecular Docking Study, 2014
- Study on the Designing and Antioxidant Properties of New N H Indole 2 Carboxamide and 3 Acetamide Derivatives and Their Activation on Heme Oxygenase, 2009
- An Evalautaion for Antioxidant Effects of New N H Indole 2 Carboxamide and 3 Acetamide Derivatives on Heme oxygenase Activity and HL60 Cells,
- Effects of Newly Sysnthesized Indole Derivatives on Proliferation Apoptosis and MMP 2 Expression of PCF 7 Human Berast Adenocarcşnoma Cells, 2015
- Newly Synthesized Indole 3 Imine 2 on Derivatives Inhibited MMP 9 mRNA Expression of Human Breast Cancer Cells, 2015
- The Effects of Newly Synthesized Indole 3 Amine Derivatives on MMP 2 Activity in Breast Cancer Cells, 2015
- YENİ PİROLOPİRİMİDİN TREVLERİNİN TASARIMI SENTEZİ VE SİTOTOKSİK AKTİVİTELERİ, 2016
- Design Novel Small Indole Derivatives as Inhibitors of Src Kinase, 2016
- Synthesis biological and computational evaluation of novel n 3 substituted benzylidene 2 oxoindolin 5 yl acetamide derivatives as inhibitors of c src tyrosıne kinase,
- Synthesis and computational evaluation of some azonaphthol benzimidazoles as inhibitors of src kinase,
- Synthesis Biological and Computational Evaluation of Novel 1 3 5 Substituted Indolin 2 one Derivatives as Inhibitors of Src Family Kinases,
- Computational evaluation of tetrahalobenzimidazoles as inhibitors of casein kinase 2,
- Evaluation of Benzimidazole Derivatives as Src Kinase and Mammalian Glutathione S Transferase Inhibitors,
- The Effects of Novel İndole Derivatives as Inhibitors of Src Kinase and Mammalian Glutathione S Transferase,
- Evaluation of Novel Indole 3 Imine 2 on Derivatives as Src Kinase and Mammalian Glutathione S Transferase Inhibitors,
- Surface display of human hyaluronidases by Autodisplay in E coli and development of a microplate assay using whole cells for screening of potential hyaluronidase inhibitors,
- Autodisplay of human hyaluronidases in E coli and development of a microplate assay for inhibitor testing at pH 7 and pH 3 5,
- Investigating Antioxidant and Src Kinase Inhibitory Effects of Aminomethylindole Derivatives,
- Investigaton The Hyaluronidase İnhibitory Activity of Aminomethyl Indole Derivatives,
- Evaluation of New N C3 and C5 Substituted Indole Derivatives as Hyaluronidase Inhibitors,
- Study on tha Designing and Antioxidant Properties of New N H Indole 2 Carboxamide and Acetamide Derivatives and their Activation Potential on Heme Oxygenase,
- Synthesis of novel 1 3 5 trisubstituted indole derivatives as inhibitors of pp60c src tyrosine kinase,
- Investigating antioxidant effects of n substitited indole 3 imine and amine derivatives as src kinase inhibitors,
- Evaluation of new indole and bromoindole derivatives as pp60c src tyrosine kinase inhibitors,
- Indole acetamides increase hyaluronic acid digestion at pH 3 5 whereas indolecarboxamides inhibit the digestion at pH 7,
- Autodisplay of Human Tumour Targets and Microplate Inhibitor Testing,
- Synthesis and antioxidant evaluation of new N H indole 2 carboxamide and acetamide derivatives,
- New Potent Indole Derivatives as hyaluronidase inhibitors,
- In vitro Antimicrobial and Antiviral Screening of 3 substituted benzylidene 1 3 dihydro indolin derivatives,
- Antimicrobial Screening of Some Indole Derivatives,
- Synthesis of 2 amino 5 substituted pyrrolo 2 3 d pyrimidine 4 3H one derivatives as tyrosine kinase inhibitors,
- Biochemical respondes of chemical compounds to free radicals,
- Synthesis of Radiolabelled 5 Aminomethyl 2l aminopyrrolo 2 3 d pyrimidine 4 3H one PreQ1 and 2 Amino 5 1S 2R 3S 2 3 dihydroxycyclopent 4 enylamino methyl pyrrolo 2 3 d pyrimidine 4 3H one,
- Evaluations of Indole Esters as Inhibitors of p60c Src Receptor Tyrosine Kinase and Investigation of Enzyme Inhibition Using Receptor Docking Studies,
- Synthesis and docking based studies of 3 substituted indolin 2 on derivatives as tyrosine kinase inhibitors,
- Anti oxidant effects of new indole derivatives,
- A study on the interaction between p60c Src receptor tyrosine kinase and arylcarboxylic and arylacetic acid derivatives based on docking modes and in vitro activity,
- Syntheses and Biological Evaluation of Indole 2 and 3 Carboxamides A New Selective Cyclooxygenase 2 Inhibitors,
- Ester Derivatives of N Substituted indoles are COX 2 Inhibitors,
- Synthesis and Biological Activity of N Substituted Indole 2 Carboxamide and 3 Acetamide Derivatives as Selective COX 2 Enzyme Inhibitors,
- Synthesis and Antiviral Activities of 2 Deoxy 2 fluoro D and L arabinofuranosyl Triazole and Imidazole Derivatives,
- Synthesis of Analgesic and Antispasmodic Active New N Substituted Indole 2 Carboxylic Acid Esters,
- Synthesis and Investigation of Some Pharmacological Activities on N Substituted Indole 2 Carboxylic Acid Esters,
- A Public Level Survey Concerning Expiration Date of Drugs,
- Studies on the Synthesis of Some Biologically Active New Benzimidazole Derivatives,
- Studies on the Synthesis of Some Biologically Active New Benzimidazole Derivatives,
- Studies on the Quantitative Analysis of Indapamide Hemyhydrate,
- Drug Repurposing in Cancer Therapy: Approaches and Applications, ISBN: 0000000, 2020
- Patrick Medisinal Kimya, ISBN: , 2019
- Kalitatif ve Kantitatif İlaç Analizleri, ISBN: , 2014
- Kalitatif ve Kantitatif İlaç Analizleri I, ISBN: , 2010
- Antiviral Nucleosides, ISBN: , 1997
- Postdoctoral Fellow, 1998
- Postdoctoral Scientist, 2000
- Visiting Professor, 2002
- Visiting Professor, 2003
- Visiting Scientist, 2003